Editing question

I use adobe lightroom, canon 30D and shoot in raw, edit them in lightroom and then upload them to photoshop in raw, edit them there, save to desktop. I have been doing it this way for years. All of the sudden my last photo shoot every time I save each picture the colors turn greyish and muted. I opened another file from a previous shoot and saved it, and it did not have this problem. I looked to see if anything was different, one said RGB/8* (that was the off colored one) The "normal" one said "RGB/8#". These were the only things that I noticed that might be different. I don't know what to do. I want to change all of the settings so the pictures look just like the ones I edited when I save them on my computer. I tried to upload them online and they looked just as terrible, so its not a problem on my desktop. Any advice would be appreciated thank you!